Today, in order to perform complex surgical procedures on the heart and associated circulatory tracts, medical professionals need a working model on which to practice various techniques. Due to the high level of trauma and health risks, many of the experiments aimed at developing new methods of cardiovascular treatment are conducted only on animals (e.g., rats).

Conducting cardiovascular research using these kinds of models requires precise research tools. To study cardiac activity, medical professionals use computer-assisted long-term signal recording techniques, which allow them to record a huge number of signals from processes occurring in the human heart, compared to conventional electrocardiography (ECG).

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LETI scientists have developed software on the Matlab platform to estimate temporal and frequency parameters. This program performs calculations according to standard methods for human research, but with correction for peculiarities of the rat body: for example, the heart rate of rats is about five times higher than that of humans. Several coefficients were adjusted to take into account these peculiarities.

The device used to measure cardiac parameters is capable of recording the parameters in two channels with a frequency of 2000 Hz. This makes it possible to collect a large amount of information on the cardiovascular system performance.